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30 Greatest Bible Verses About Depression & How to Cope With Feeling Hopeless

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In this world, many sad and difficult things can happen every day. Each day presents us with different challenges, and at times, these struggles can make us feel overwhelmed or discouraged. Feelings of sadness can sometimes develop into anxiety and, in more severe cases, lead to depression. Depression is a common condition, and no one should feel ashamed for experiencing it. Instead of judging or discriminating against those who struggle with mental health, we should offer support, encouragement, and positivity. A kind word or a helping hand can make a significant difference in someone’s life. If you are experiencing depression, do not lose hope. Remember that God loves you unconditionally and wants to help you through your struggles.

Here are some Bible verses about depression, as well as a list of Bible verses to read when you are feeling depressed. They can provide comfort, strength, and guidance for those facing depression. Be sure to share these with your family, friends, or anyone who might be struggling with sadness or hardship. These quotes from the Bible can serve as a source of hope and encouragement, helping individuals find peace and rediscover joy in their lives.

30 Bible Verses to Read When You’re Struggling With Depression

15 Bible Verses About Depression

Psalm 34:18 – “The Lord is close to the brokenhearted and saves those who are crushed in spirit.”

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Lamentations 3:19-20 – “I remember my affliction and my wandering, the bitterness and the gall. I well remember them, and my soul is downcast within me.”

Job 3:26 – “I have no peace, no quietness; I have no rest, but only turmoil.”

Psalm 143:7-8 – “Answer me quickly, Lord; my spirit fails. Do not hide your face from me or I will be like those who go down to the pit.”

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1 Kings 19:4 – “I have had enough, Lord,” he said. “Take my life; I am no better than my ancestors.”

Jeremiah 20:14 – “Cursed be the day I was born! May the day my mother bore me not be blessed!”

Psalm 42:11 – “Why, my soul, are you downcast? Why so disturbed within me? Put your hope in God, for I will yet praise him, my Savior and my God.”

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Jonah 2:2 – “In my distress I called to the Lord, and he answered me. From deep in the realm of the dead I called for help, and you listened to my cry.”

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Ecclesiastes 1:2 – “‘Meaningless! Meaningless!’ says the Teacher. ‘Utterly meaningless! Everything is meaningless.'”

Psalm 102:1-3 – “Hear my prayer, Lord; let my cry for help come to you. Do not hide your face from me when I am in distress.”

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Psalm 77:2-3 – “When I was in distress, I sought the Lord; at night I stretched out untiring hands, and I would not be comforted.”

Isaiah 53:3 – “He was despised and rejected by mankind, a man of suffering, and familiar with pain.”

Matthew 26:38 – “Then he said to them, ‘My soul is overwhelmed with sorrow to the point of death. Stay here and keep watch with me.'”

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Psalm 6:6 – “I am worn out from my groaning. All night long I flood my bed with weeping and drench my couch with tears.”

2 Corinthians 1:8 – “We were under great pressure, far beyond our ability to endure, so that we despaired of life itself.”

15 Bible Verses to Help with Depression

Matthew 11:28 – “Come to me, all you who are weary and burdened, and I will give you rest.”

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Isaiah 41:10 – “So do not fear, for I am with you; do not be dismayed, for I am your God. I will strengthen you and help you; I will uphold you with my righteous right hand.”

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2 Corinthians 12:9 – “But he said to me, ‘My grace is sufficient for you, for my power is made perfect in weakness.'”

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Philippians 4:6-7 – “Do not be anxious about anything, but in every situation, by prayer and petition, with thanksgiving, present your requests to God.”

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Psalm 55:22 – “Cast your cares on the Lord and he will sustain you; he will never let the righteous be shaken.”

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Romans 8:28 – “And we know that in all things God works for the good of those who love him.”

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Psalm 30:5 – “Weeping may stay for the night, but rejoicing comes in the morning.”

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John 16:33 – “In this world you will have trouble. But take heart! I have overcome the world.”

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Psalm 147:3 – “He heals the brokenhearted and binds up their wounds.”

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Deuteronomy 31:8 – “The Lord himself goes before you and will be with you; he will never leave you nor forsake you. Do not be afraid; do not be discouraged.”

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Joshua 1:9 – “Be strong and courageous. Do not be afraid; do not be discouraged, for the Lord your God will be with you wherever you go.”

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Romans 15:13 – “May the God of hope fill you with all joy and peace as you trust in him, so that you may overflow with hope by the power of the Holy Spirit.”

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1 Peter 5:7 – “Cast all your anxiety on him because he cares for you.”

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Psalm 23:4 – “Even though I walk through the darkest valley, I will fear no evil, for you are with me.”

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Isaiah 61:3 – “He will give a crown of beauty instead of ashes, the oil of joy instead of mourning, and a garment of praise instead of a spirit of despair.”

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Final Thoughts About These Bible Verses About Depression

We hope you were able to resonate with these Bible verses about depression, and that they could provide you with some peace and comfort. Every time you feel sad, need comfort or seek encouragement, feel free to revisit this list of quotes from the Bible for inspiration. 

If you are struggling with depression, do not lose faith. Always remember that your family and friends love and care for you deeply. They want to support and help you through your difficult times. Most importantly, our Heavenly Father loves each one of us unconditionally and offers His comfort through His Word. 

Studying and meditating on God’s Word is one of the best ways to overcome depression. Whether you are feeling sad, discouraged, or even at peace, always take time to read the Bible and trust in God. His promises bring hope and strength, reminding us that no hardship will last forever. These Bible verses are perfect for personal reflection, sharing in messages or cards, and posting on your Social Media to spread positivity and encouragement—especially to those who are feeling down. Remember, every difficult season will pass, and a brighter future awaits when we put our trust in God and allow Him to be our guide in our lives.


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